Epilogue
Mom
Depths II and its variants
Defeat Mom for the first time.
- Standard access
- Reach the Chapter 3 finale.
Mom is the first major milestone, but has no separate completion-mark slot.
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Repentance · Epilogue and all 22 numbered endings
Ending requirements
Match the number in the Stats menu to its target and route. This guide gives the requirements without retelling the cutscenes.
An ending and a completion mark record different things
Endings belong to the save
The ending list is shared across the save file. You do not need to unlock all 22 again with every character.
Marks belong to a character
The same target can still earn a missing character mark. Hard clears and Greedier affect the mark level and its rewards.
A checkpoint can lead onward
A photograph can turn Isaac's or Satan's chest into a route onward. Look up unlocked cutscenes in the in-game Stats menu.
Use an ordinary eligible run for these save milestones. Challenges, seeded runs and special run types can have their own unlock restrictions.
The first save milestones
Mom, then eleven Mom's Heart clears
Endings 1–11
Mom's Heart
Womb II and its variants
The first eleven clears advance this sequence across your save. Changing character does not restart it. Unlock the Womb by defeating Mom.
- Ending 1Mom's Heart clear 1
- Ending 2Mom's Heart clear 2
- Ending 3Mom's Heart clear 3
- Ending 4Mom's Heart clear 4
- Ending 5Mom's Heart clear 5
- Ending 6Mom's Heart clear 6
- Ending 7Mom's Heart clear 7
- Ending 8Mom's Heart clear 8
- Ending 9Mom's Heart clear 9
- Ending 10Mom's Heart clear 10
- Ending 11Mom's Heart clear 11
The eleventh clear unlocks It Lives!, which replaces Mom's Heart in ordinary runs. These eleven endings are not eleven separate mark slots.
Main branches
Choose the upper or lower route
Isaac and Satan are separate targets. The Polaroid and The Negative open the standard routes beyond them.
Ending 12
Satan
Sheol
Defeat Satan.
- Standard access
- Use the Sheol exit after Mom's Heart or It Lives!.
- Related character mark
- Satan
The Negative can make the post-fight chest continue to the Dark Room.
Ending 13
Isaac
Cathedral
Defeat Isaac.
- Standard access
- Use the Cathedral exit after Mom's Heart or It Lives!.
- Related character mark
- Isaac
The Polaroid can make the post-fight chest continue to the Chest.
Ending 14
??? (Blue Baby)
Chest
Defeat ??? (Blue Baby).
- Standard access
- Unlock The Polaroid by defeating Isaac five times.
- Related character mark
- ??? (Chest)
Ending 15
The Lamb
Dark Room
Defeat The Lamb.
- Standard access
- Unlock The Negative by defeating Satan five times.
- Related character mark
- The Lamb
Ending 16
Mega Satan
Chest or Dark Room
Defeat Mega Satan.
- Standard access
- Defeat ??? or The Lamb once, then prepare an opener for the golden door.
- Related character mark
- Mega Satan
Repentance can end the run immediately here. Finish other available targets first if you want their marks in the same run.
Optional finales
Hush and Delirium
The first Hush clear unlocks an ending and opens The Void. Later runs can use that route to pursue Delirium.
Ending 17
Hush
Blue Womb (??? floor)
Defeat Hush for the first time.
- Standard access
- Unlock Blue Womb after ten Mom's Heart clears, then reach its timed entrance.
- Related character mark
- Hush
The usual entrance needs the Womb boss defeated before 30 minutes. Later Hush clears can continue through the available exits.
Ending 20
Delirium
The Void
Defeat Delirium.
- Standard access
- Defeat Hush once to unlock The Void, then enter a Void portal.
- Related character mark
- Delirium
The Hush route provides the reliable portal used by our route planner.
Greed modes
Two endings, one Greed mark slot
Choose the mode before the run. Greedier adds a second boss phase and uses the higher completion level.
Ending 18
Ultra Greed
Greed Mode finale
Defeat Ultra Greed in Greed Mode.
- Standard access
- Choose Greed Mode when starting the run.
- Related character mark
- Greed
Greed Mode has a separate floor sequence from an ordinary run.
Ending 19
Ultra Greedier
Greedier Mode finale
Defeat Ultra Greedier in Greedier Mode.
- Standard access
- Donate 500 coins to the Greed Donation Machine to unlock Greedier.
- Related character mark
- Greedier
Greedier records the higher level of the shared Greed completion-mark slot.
Repentance finales
Mother and The Beast are different finales
Mother is at the end of the alternate floor route. The Beast is reached through the Ascent and Home.
Ending 21
Mother
Corpse II
Defeat Mother.
- Standard access
- Defeat Hush three times to unlock A Secret Exit, then complete the Knife Piece route.
- Related character mark
- Mother
#100
Ending 22
The Beast
Home
Defeat The Beast.
- Standard access
- Defeat Mother once to unlock A Strange Door, then follow the Ascent to Home.
- Related character mark
- The Beast
Turn the missing ending into a run goal
Check the save gate, prepare the route, then pick a character whose target mark is still missing. You can work toward the ending and a character reward in the same run.
Requirements reviewed October 8, 2026 for Repentance. Access notes describe standard routes; special items can create exceptions. Original boss and mark art is reused. See the ending reference and the gameplay sources linked in our route guides.