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Isaac hub

New player run goals

Run goals and completion marks explained

Pick a character, choose one reachable destination, and let that goal decide which exit or timer matters. The post-it note on the character select screen records the completion marks you earn.

Prepare for the next floor

Read floor access, checkpoint and exit rules, then compare the mode that matches your completion goal.

The basic idea

A run can have a purpose.

Marks belong to characters

Defeating a target fills its mark for the character you used. Try the same target with another character to record that character's mark.

Normal and Hard

A Hard clear counts for both Hard and Normal. Greed Mode has its own slot, with Greedier as the higher clear level.

Routes and timers change the plan

Some goals depend on the exit you take. Boss Rush and Hush use time limits. Choose your main destination before the run so you know which gate to prepare for.

You can earn more than one mark in a run when the route allows it. There is no need to chase every mark at once.

A simple starting plan

Choose a target you can reach now.

These are useful milestones for a new save. You can take the upper or lower route first once they become available.

First destination

Mom's Heart

Learn the floors and aim to clear the Womb boss with one character.

See the mark
When the exits open

Isaac or Satan

Choose Cathedral for Isaac or Sheol for Satan. Each is its own character mark.

After the photographs

Chest or Dark Room

The Polaroid leads toward ???; The Negative leads toward The Lamb.

See the save-file unlock gates

Choose your destination

What each completion mark asks you to do

The 12 tracker targets are grouped by main paths, timed objectives, Repentance routes, and Greed Mode. The unlocks required to reach later paths are shared across the save file; the marks themselves are recorded for each character.

Each card shows the mark as it appears for a Normal and Hard clear. Greed and Greedier use the same slot. Delirium changes the paper itself.

Main routes

Completion mark

Mom's Heart / It Lives!

Normal
Hard

Reach Womb II and defeat Mom's Heart or It Lives! with the character you chose.

A clear first destination while you learn the floors. Repeated Heart wins also open later routes across the save file.

Completion mark

Isaac

Normal
Hard

After the Womb boss, take the Cathedral beam and defeat Isaac.

This is the upper main path. Isaac wins eventually unlock The Polaroid, which lets you continue to Chest.

Completion mark

??? (Chest)

Normal
Hard

Take The Polaroid after Mom, defeat Isaac, enter Chest, and defeat ??? (Blue Baby).

Choose this after you have opened the Polaroid route.

Completion mark

Satan

Normal
Hard

After the Womb boss, take the Sheol trapdoor and defeat Satan.

This is the lower main path. Satan wins eventually unlock The Negative, which lets you continue to Dark Room.

Completion mark

Mega Satan

Normal
Hard

Prepare a way through the golden door in Chest or Dark Room and defeat Mega Satan.

This is an extra Chapter 6 goal. Check the door unlock and Key Piece steps before planning the run.

Timed & optional

Completion mark

Boss Rush

Normal
Hard

On the standard path, defeat Mom and enter the Boss Rush room before 20 minutes, then clear its waves.

This is a timed side objective. It is separate from the ending boss you choose afterward. Mausoleum/Gehenna uses a 25-minute entrance instead.

Completion mark

Hush

Normal
Hard

After the Blue Womb entrance is unlocked, defeat the Womb boss before 30 minutes, enter Blue Womb, and defeat Hush.

The entrance unlocks after ten Mom's Heart victories across the save file. This is a timed goal, so plan for it before starting.

Completion mark

Delirium

Normal
Hard

Reach the Void and defeat Delirium with your chosen character.

The route planner follows Hush into the Void. Other major-boss portals can also provide an entrance.

Repentance routes

Completion mark

Mother

Normal
Hard

Collect both Knife Pieces, open the flesh door, reach Corpse II, and defeat Mother.

This is a separate Repentance route unlocked after three Hush victories across the save file.

Completion mark

The Beast

Normal
Hard

Open A Strange Door, take Dad's Note, complete the Ascent, and defeat The Beast at Home.

This route becomes available after a Mother victory. It leaves the normal downward path on Depths II.

Greed mode

Completion mark

Greed / Greedier

Greed
Greedier

Start a separate Greed Mode run and defeat Ultra Greed. Later, clear Greedier Mode for the higher level of this mark.

Greed and Greedier share one tracker slot. This does not use the standard floor route.

Record the clear

Pick the character you played and set the mark to Normal or Hard. The tracker is manual and stays in this browser unless you export a backup.

Open tracker

Plan the next route

If the goal needs a special door, photograph, Knife Piece, or timed entrance, follow the route checkpoints before starting.

Open route planner

This guide targets the supplied Repentance data. Special items and unusual exits can change a route. See the completion-mark reference for rules and exceptions.