RuneChallenge #1
Hagalaz
Destruction
What it does
Breaks obstacles in the current room, apart from indestructible blocks and pillars.
Isaac hub
Repentance challenge rewards
Challenge pocket rewards
A challenge can unlock more than an item. Explore the runes, cards, and pill effects you can add to future runs, and see what each one does.
9 Runes
Nine rune effects to unlock
10 Cards
Ten special cards to discover
4 Pill effects
Four effects from two challenges
Reviewed effects
Find what a challenge unlocks
Search by reward, effect, or challenge. Follow any unlock link to see the challenge behind it.
RuneChallenge #2
Jera
Abundance
What it does
Duplicates pickups and chests in the room. It does not duplicate item pedestals.
RuneChallenge #3
Ehwaz
Passage
What it does
Opens a trapdoor to the next floor. On a special floor tile, it opens a Crawl Space instead.
RuneChallenge #4
Dagaz
Purity
What it does
Grants one Soul Heart and removes most curses from the current floor.
RuneChallenge #5
Ansuz
Vision
What it does
Reveals the floor map, apart from the Ultra Secret Room.
RuneChallenge #6
Perthro
Change
What it does
Rerolls the item pedestals in the current room, like The D6.
RuneChallenge #20
Berkano
Companionship
What it does
Spawns three friendly Blue Flies and three Blue Spiders.
RuneChallenge #8
Algiz
Resistance
What it does
Grants a protective shield for 20 seconds.
RuneChallenge #30
Blank Rune
???
What it does
Activates a random rune effect and has a chance to spawn another Blank Rune.
CardChallenge #9
Chaos Card
???
What it does
Throws a card that destroys most enemies and obstacles in its short path. Some bosses and phases are exceptions.
CardChallenge #10
Credit Card
Charge it!
What it does
Removes prices from purchases in the current room, including heart costs.
CardChallenge #11
Rules Card
???
What it does
Displays a random fortune-style message, which can contain a hint or special seed.
CardChallenge #12
A Card Against Humanity
Something stinks...
What it does
Fills the current room with poop.
CardChallenge #7
Suicide King
A true ending?
What it does
Kills Isaac immediately, then spawns ten pickups and/or items from the current room's pool.
CardChallenge #22
Get Out Of Jail Free Card
Open Sesame
What it does
Opens all doors in the current room, like Dad's Key.
CardChallenge #42
VII - The Chariot?
May nothing walk past you
What it does
Turns Isaac into an invulnerable, slightly movable statue with four times his fire rate for ten seconds.
CardChallenge #43
VIII - Justice?
May your sins come back to torment you
What it does
Spawns two to four Locked Chests nearby.
CardChallenge #44
IX - The Hermit?
May you see the value of all things in life
What it does
Sells items and pickups on the ground for coins based on their shop value. Spawns a penny if there is nothing to sell.
CardChallenge #45
XIV - Temperance?
May your hunger be satiated
What it does
Forces Isaac to consume five random pill effects immediately. Those effects can be harmful.
Pill effectChallenge #24
Percs!
What it does
Grants The Wafer's damage reduction for the current room.
Pill effectChallenge #24
Addicted!
What it does
Makes all damage count as one full heart for the current room.
Pill effectChallenge #25
Re-Lax
What it does
Makes Isaac leave poop behind while moving for a short time.
Pill effectChallenge #25
???
What it does
Applies Curse of the Maze for the rest of the floor.
These are the challenge-linked rewards from the supplied Repentance data. The illustrations show their in-game unlock achievements. Effects are reviewed summaries linked to detailed references. Recorded clears come from your browser checklist and do not read your game save.
See all 45 challenges