The final hit can start a new threat
A death can send out shots or release more enemies. Watch the space around the final hit before crossing it.
The Binding of Isaac / Enemies
Repentance · Ordinary enemies
Enemy survival guides
A small enemy can end a good run if you miss its firing lane, death effect or vulnerable window. Start with 48 useful references and learn the differences between similar-looking variants.
Twelve more enemies to recognize
Death bursts, falling hands, and deceptive pauses
Learn what changes after a final hit, a disappearing body, or a brief pause. Compare each illustrated example with the related threats.
Dodge the charge, then check the blast
Leave a Leech's charge lane sideways, give its exploding variant distance, and use a falling hand's shadow to leave its landing area.
Read what the pause means
A Stoney's rest is not a damage window. A Mushroom's open cap is, while a shrinking Boil still needs to be finished.
Find the next firing origin
A worm can resurface elsewhere, a Maw drifts closer, and a Fat Bat seeks a diagonal angle. Recheck the attacker before choosing your next dodge.
Beyond the first familiar rooms
New threats as your routes open up
Later floors and alternate paths add new reasons to change your position or target. These four lessons connect the later encounter references.
Leave the laser lane
Step off the firing axis. Getting behind Double Vis still leaves you on one of its two beams.
Find the attacker again
A teleport changes the origin of the next attack. Look for the reappearance before committing to your dodge.
Remove the room's protection
Bishops shield other enemies. Find the support enemy while keeping clear of protected pursuers and shooters.
Watch the space around the body
A new burrowing lump, toxic gas or a moving burst origin can make an apparently empty route dangerous.
Find the enemy. Read its threat.
Search a name, entity ID or behavior. Pattern filters describe the main lesson for each record, rather than every possible attack.
Showing 48 of 48 enemies
Babies
Angelic Baby
A winged Baby with a three-shot spread and frequent teleports.
Spread shots25 base HPID 38.1
Attack cues and response Flies
Attack Fly
A red fly that follows you and hurts on contact.
Pursuers5 base HPID 18.0
Attack cues and response Babies
Baby
A floating shooter that can relocate by teleporting.
Shooters25 base HPID 38.0
Attack cues and response Spiders
Big Spider
A larger spider that leaves two smaller threats.
Pursuers20 base HPID 94.0
Attack cues and response Bishops
Bishop
A stationary support enemy that shields the rest of the room.
Room supportFloor-scaled HPID 805.0
Attack cues and response Knights
Black Knight
A Knight variant that reflects tears and creates fire waves.
Guarded targets30 base HPID 41.4
Attack cues and response Boils
Boil
A stationary growth that shrinks under damage and swells again.
Regenerators20 base HPID 30.0
Attack cues and response Skeletons
Bony
A skeleton that quickly throws bones when you line up.
ShootersFloor-scaled HPID 227.0
Attack cues and response Flies
Boom Fly
A bouncing fly whose death causes an explosion.
Death hazardsFloor-scaled HPID 25.0
Attack cues and response Maggots
Charger
A crawler that turns alignment into a fast charge.
Line charges20 base HPID 23.0
Attack cues and response Clots
Clot
A dark clot whose shots travel diagonally.
Spread shots15 base HPID 15.1
Attack cues and response Clots
Clotty
A wandering clot that attacks along four straight lanes.
Spread shots15 base HPID 15.0
Attack cues and response Vis
Double Vis
A Vis variant that fires a laser from both sides.
Laser lanes25 base HPID 39.1
Attack cues and response Bats
Fat Bat
A flying enemy that seeks a diagonal firing angle.
Shooters35 base HPID 258.0
Attack cues and response Flies
Fly
A harmless-contact fly that can become a shooting enemy.
Passive bodies3 base HPID 13.0
Attack cues and response Gapers
Frowning Gaper
A pursuer that speeds up after seeing Isaac.
Pursuers10 base HPID 10.0
Attack cues and response Gapers
Gaper
A slow pursuer that can leave another enemy behind.
Pursuers10 base HPID 10.1
Attack cues and response Gasbags
Gasbag
A Corpse enemy surrounded by toxic gas that also sends out flies.
Area hazards80 base HPID 856.0
Attack cues and response Globins
Globin
A regenerating pursuer that must be finished on the ground.
Regenerators33 base HPID 24.0
Attack cues and response Clots
Grilled Clotty
A fast charred Clotty with slightly angled four-way shots.
Spread shots20 base HPID 15.3
Attack cues and response Jumpers
Hopper
A hopping enemy that closes in when you approach.
Jumpers10 base HPID 29.0
Attack cues and response Horfs
Horf
A stationary enemy that shoots when you enter range.
Shooters10 base HPID 12.0
Attack cues and response Hosts
Host
A skull-covered enemy with a brief vulnerable window.
Guarded targets14 base HPID 27.0
Attack cues and response Clots
I.Blob
A clot variant that combines straight and diagonal shots.
Spread shots15 base HPID 15.2
Attack cues and response Leeches
Kamikaze Leech
A Leech that adds an explosion when it dies.
Death hazards25 base HPID 55.1
Attack cues and response Knights
Knight
A charging enemy whose front blocks ordinary tears.
Guarded targets20 base HPID 41.0
Attack cues and response Leeches
Leech
A flying charger that commits when you share a row or column.
Line charges25 base HPID 55.0
Attack cues and response Maws
Maw
A drifting head that approaches while firing an aimed shot.
Shooters20 base HPID 26.0
Attack cues and response Mom's Hands
Mom's Hand
A falling hand that can send Isaac back to the floor entrance.
Jumpers20 base HPID 213.0
Attack cues and response Mulligans
Mulligan
A fleeing enemy that leaves flies behind when it dies.
Death hazards13 base HPID 16.0
Attack cues and response Hosts
Mushroom
A capped enemy with reduced damage intake while hiding.
Guarded targets23 base HPID 300.0
Attack cues and response Burrowers
Needle
A burrowing lunger whose warning lump can move between attacks.
JumpersFloor-scaled HPID 881.0
Attack cues and response Pooters
Pooter
A drifting fly that fires single aimed shots.
Shooters8 base HPID 14.0
Attack cues and response Flies
Red Boom Fly
A Boom Fly variant that releases a ring of shots.
Death hazardsFloor-scaled HPID 25.1
Attack cues and response Ghosts
Red Ghost
A teleporting ghost that replaces Wizoob shots with a laser.
Laser lanesFloor-scaled HPID 285.0
Attack cues and response Hosts
Red Host
A Host variant you can damage even while lowered.
Spread shots15 base HPID 27.1
Attack cues and response Maws
Red Maw
A faster Maw whose final hit triggers a four-way shot burst.
Death hazards20 base HPID 26.1
Attack cues and response Skeletons
Revenant
A skeleton that replaces bone throws with a short stream of fire.
ShootersFloor-scaled HPID 841.0
Attack cues and response Burrowers
Round Worm
A burrowing shooter that changes the origin of its next shot.
Shooters10 base HPID 244.0
Attack cues and response Spiders
Spider
An erratic crawler that rushes nearby targets.
Pursuers6.5 base HPID 85.0
Attack cues and response Maggots
Spitty
A crawling shooter whose facing direction matters.
Shooters10 base HPID 31.0
Attack cues and response Gapers
Stoney
An invulnerable pursuer that blocks shots without ordinary contact damage.
Shot blockersInvulnerable bodyID 302.0
Attack cues and response Flies
Sucker
A slow pursuing fly with a four-way death burst.
Death hazards10 base HPID 61.0
Attack cues and response Pooters
Super Pooter
A Pooter variant with a two-shot spread.
Spread shots8 base HPID 14.1
Attack cues and response Jumpers
Trite
A jumping spider with long, sudden leaps.
Jumpers10 base HPID 29.1
Attack cues and response Vis
Vis
An opened torso that fires a laser when you line up.
Laser lanes25 base HPID 39.0
Attack cues and response Whippers
Whipper
A charging enemy with a short whip that can deflect tears.
Line charges35 base HPID 834.0
Attack cues and response Ghosts
Wizoob
A disappearing ghost that returns near you with spectral shots.
Spread shotsFloor-scaled HPID 219.0
Attack cues and response Similar family. Different gaps.
Clotty, Clot and I.Blob are different dodges.
These diagrams show firing directions relative to the enemy. Real rooms add movement, obstacles and other attackers, so a gap in one pattern is not a guarantee of safety.
A practical opening check
Read the whole room before choosing a target.
- Find an escape lane. Notice where a pursuer or jumper can cut you off, and leave room to change direction.
- Check what can fire across that lane. A distant shooter can matter more than a nearby harmless body.
- Look for room support. If enemies have shields, find the Bishops sustaining that protection while keeping a safe path around the room.
- Read the final hit. Explosions, projectile rings, new enemies and a regenerating pile can leave the space dangerous after a body falls.
- Choose an angle or window. Reposition around a guarded target while watching the rest of the room. Continuous shooting is not always the fastest safe finish.
These are suggested responses, not a fixed priority list. Your character, weapon, room layout and remaining health can change the best target.
Patterns worth learning early
Pursuers
Keep an escape route open as the enemy closes in.
Example: GaperShooters
Read the firing direction before crossing its lane.
Example: HorfSpread shots
Find the gaps between shots, and check the variant.
Example: Super PooterDeath hazards
Leave room for the hazard triggered by the final hit.
Example: Boom FlyGuarded targets
A vulnerable angle or window matters more than continuous fire.
Example: HostJumpers
Follow the landing lane as well as the current position.
Example: HopperRegenerators
Finish the remaining stage before it recovers.
Example: GlobinLine charges
Cross the committed charge lane rather than retreating along it.
Example: ChargerPassive bodies
A harmless body can transform into a different threat.
Example: FlyLaser lanes
Leave the firing axis before the beam fills it.
Example: VisArea hazards
Keep your escape route outside the lingering hazard.
Example: GasbagRoom support
Find the enemy sustaining the shield before attacking protected targets.
Example: BishopShot blockers
Move around the invulnerable body and defeat the enemies keeping the room locked.
Example: StoneyHealth, champions and mode changes
Base HP comes from the supplied Repentance entity definition. A positive stage-health field means the floor changes health, so the directory labels it as floor-scaled. Champions, variants and other modifiers can change the encounter further. A champion's pickup drop is separate from the room-clear award; Hard and Greed also have their own reward rules.
A curated reference for 48 enemies, reviewed October 7, 2026 for Repentance. It is not an exhaustive bestiary or a floor spawn table. Pattern diagrams are explanatory schematics. Gameplay references and the corresponding entity definition are documented on each detail page. Repentance+ and mods can differ.