Isaac hub / Gameplay reference

Repentance pickup guide

Pickups and chests

Learn which hearts heal you, how much each coin is worth, and whether that chest needs a key, a bomb, or a health payment.

Browse 48 pickups

Want to understand why a drop appeared? Read room-clear rewards, luck and reward-changing items.

New player health guide

A heart can mean several things.

These are dropped pickups, while the HUD shows the health you already hold. Use the character healing helper to check whether a pickup refills health, adds a new type, or becomes another resource. Special characters use different health rules, so check the character stats guide and HUD guide when the result looks different.

What does this chest cost?

Compare the opening rule before you commit. Open an entry for its reward possibilities, original chest previews, and related item pools.

Compare all 12 chest types
Repentance chest opening costs and main hazards
ChestOpening ruleMain consideration
Chest in-game pickup
Chest
Free to openCheck for a Mimic or Haunted Chest before walking into a similar-looking chest.
Locked Chest in-game pickup
Locked Chest
Costs 1 keyAn item is possible, but it is not guaranteed.
Bomb Chest in-game pickup
Bomb Chest
Needs an explosionStand clear of the blast used to open it.
Spiked Chest in-game pickup
Spiked Chest
Normally costs ½ heartBudget for the health payment before touching the spikes.
Mimic Chest in-game pickup
Mimic Chest
Becomes spiked when approachedApproaching it can turn an apparently free chest into a health payment.
Eternal Chest in-game pickup
Eternal Chest
1 key per openingRepeated openings spend more keys, and the sequence can end without another reward.
Old Chest in-game pickup
Old Chest
Costs 1 keyIt requires a key even though its worn appearance differs from a golden chest.
Wooden Chest in-game pickup
Wooden Chest
Free to openOpening it does not identify an unknown pill's effect for you.
Mega Chest in-game pickup
Mega Chest
Costs 1–7 keysOne key may only make progress toward opening it.
Haunted Chest in-game pickup
Haunted Chest
Ghost throws it before it opensThe closed or thrown chest deals half a heart of damage on contact.
Red Chest in-game pickup
Red Chest
Free opening; risky contentsBe ready to move as soon as it opens.
Mom's Chest in-game pickup
Mom's Chest
Free; found in HomeIts first-opening reward does not repeat on every Home run.

Troll Bombs are live hazards. Golden Batteries hurt you on collection. Red Chests can release enemies or explosives. Read the opening rule even when something looks like a reward.

Pickup directory

Identify what dropped.

48 of 48 pickups

Red Heart in-game pickup

Hearts

Red Heart

Heals existing red health. It does not add another heart container.

Value / opening cost
Refills up to 1 red heart
Before you collect
You need missing red health to benefit from ordinary red-heart healing.
Effects, rules & related guides

A paired pickup that restores as much as two full red hearts.

Value / opening cost
Refills up to 2 red hearts
Before you collect
Healing is limited by the empty red containers you already have.
Effects, rules & related guides

Adds blue health that is consumed when damaged rather than leaving an empty refillable container.

Value / opening cost
Adds 1 temporary heart
Before you collect
Red Heart pickups cannot refill a Soul Heart after it is lost.
Effects, rules & related guides

The half-size version of a Soul Heart, with the same non-refillable health behavior.

Value / opening cost
Adds ½ temporary heart
Before you collect
It grants half a heart of protection, not a permanent container.

Unlock: Defeat Mom's Heart 5 times.

Effects, rules & related guides

Temporary black health with a room-wide damage effect when the heart is depleted.

Value / opening cost
Adds 1 temporary heart
Before you collect
The damage burst happens when the heart is lost, not when you collect it.
Effects, rules & related guides

A white half-heart that becomes a red heart container if carried to the next floor or paired with another Eternal Heart.

Value / opening cost
Potential new red container
Before you collect
Protect it until you finish the floor; it has not yet become permanent red capacity.
Effects, rules & related guides

Places a golden outline around the last heart. Breaking the covered heart releases coins and briefly gilds nearby enemies.

Value / opening cost
Coin effect; no extra health
Before you collect
The outline adds no protection or heart container.

Unlock: Complete challenge #21, XXXXXXXXL.

Effects, rules & related guides

Heals like a full Red Heart but moves away when you approach.

Value / opening cost
Refills up to 1 red heart
Before you collect
Its appearance is very close to an ordinary Red Heart; movement is the useful clue.

Unlock: Quick-restart 7 times consecutively.

Effects, rules & related guides

Uses your current health to decide between red-heart healing and Soul Heart health.

Value / opening cost
Red healing or blue health
Before you collect
Missing red health takes priority over gaining blue health.
Effects, rules & related guides

Adds a bone shell that can hold red health. Once its red filling is gone, another damaging hit can break the shell.

Value / opening cost
Adds an empty bone container
Before you collect
A broken shell is lost; a Red Heart can refill its contents but cannot recreate it.

Unlock: Unlock The Forgotten.

Effects, rules & related guides

Fills a red container with rotten health that produces Blue Flies after room clears.

Value / opening cost
Red health with fly generation
Before you collect
A whole rotten heart disappears in one damaging hit.

Unlock: Enter Corpse for the first time.

Effects, rules & related guides
Penny in-game pickup

Coins

Penny

The standard one-cent coin used for purchases and coin payments.

Value / opening cost
+1¢
Before you collect
A coin's appearance matters: other variants have different values or effects.
Effects, rules & related guides
Dime in-game pickup

Coins

Dime

A silver coin worth ten cents.

Value / opening cost
+10¢
Before you collect
Count the value rather than the number of coin sprites on the floor.
Effects, rules & related guides

A penny that also increases your luck stat for the current run.

Value / opening cost
+1¢ and +1 luck
Before you collect
The luck increase is separate from its one-cent money value.

Unlock: Donate 2¢ to the Greed Donation Machine.

Effects, rules & related guides

A nickel stuck to the floor until an explosion loosens it.

Value / opening cost
+5¢ after an explosion
Before you collect
Compare five cents with the value of the bomb you would spend.

Unlock: Complete Boss Rush as Keeper.

Effects, rules & related guides

Reappears elsewhere in the same room after collection until it eventually vanishes.

Value / opening cost
+1¢ per collection
Before you collect
Repeated payouts are possible, but the coin is not infinite.

Unlock: Defeat Mega Satan as Tainted Keeper.

Effects, rules & related guides
Key in-game pickup

Keys

Key

Adds a key for locked doors and chests.

Value / opening cost
+1 key
Before you collect
Using your last key on a chest can leave an important room locked.
Effects, rules & related guides

A paired key pickup that adds two ordinary keys.

Value / opening cost
+2 keys
Before you collect
It increases your key count; it does not give the floor-long Golden Key effect.
Effects, rules & related guides

Provides unlimited key use for the remainder of the current floor.

Value / opening cost
Unlimited keys on this floor
Before you collect
The benefit ends when you leave the floor.
Effects, rules & related guides

Combines an ordinary key with active-item recharge.

Value / opening cost
+1 key and 6 charge units
Before you collect
The key and recharge are separate benefits; a full active item may not need the charge.

Unlock: Complete challenge #33, Pokey Mans.

Effects, rules & related guides
Bomb in-game pickup

Bombs

Bomb

Adds a bomb to your inventory for walls, obstacles, chests, or combat.

Value / opening cost
+1 bomb
Before you collect
Collecting the pickup is safe; the explosion from a placed bomb can hurt you.
Effects, rules & related guides

Adds two bombs to your inventory from one paired pickup.

Value / opening cost
+2 bombs
Before you collect
A large moving Megatroll Bomb is a hazard, not this inventory pickup.
Effects, rules & related guides

Lets you place unlimited bombs until you move to another floor.

Value / opening cost
Unlimited bombs on this floor
Before you collect
Unlimited supply does not protect you from your own explosions.

Unlock: Complete challenge #23, Blue Bomber.

Effects, rules & related guides

Appears with its fuse already burning and explodes instead of becoming a stored bomb.

Value / opening cost
Live explosive; no inventory gain
Before you collect
Move away. It cannot be collected as an ordinary bomb.
Effects, rules & related guides

A live bomb that moves toward Isaac when he is close enough.

Value / opening cost
Moving explosive hazard
Before you collect
Keep moving away from it; touching it will not add bombs to your inventory.
Effects, rules & related guides

A live golden bomb that keeps exploding, rather than granting unlimited bomb inventory.

Value / opening cost
Repeated explosive hazard
Before you collect
It cannot be collected. Keep clear of repeated explosions.

Unlock: Complete challenge #23, Blue Bomber.

Effects, rules & related guides

Adds a special bomb with a much larger environmental effect than an ordinary bomb.

Value / opening cost
+1 Giga Bomb
Before you collect
Once placed, its blast can damage you and create pits in the floor.
Effects, rules & related guides
Lil' Battery in-game pickup

Batteries

Lil' Battery

The regular battery pickup, adding six units of active-item charge.

Value / opening cost
+6 charge units
Before you collect
Six charge units are not a universal full refill for every item.
Effects, rules & related guides
Mega Battery in-game pickup

Batteries

Mega Battery

Fully charges active items and adds an additional full charge in reserve.

Value / opening cost
Full charge plus an overcharge
Before you collect
Its behavior is different from a fixed two- or six-unit battery.
Effects, rules & related guides

Recharges the active item, damages Isaac, and reappears in another room on the current floor.

Value / opening cost
+6 charge units; costs 1 heart
Before you collect
Collecting it deals a full heart of damage.

Unlock: Defeat Mega Satan as Tainted Forgotten.

Effects, rules & related guides
Chest in-game pickup

Chests

Chest

The ordinary brown chest opens without spending a resource and contains random pickups.

Value / opening cost
Free to open
Before you collect
Check for a Mimic or Haunted Chest before walking into a similar-looking chest.
Effects, rules & related guides

A golden chest that consumes a key and can pay out pickups or a Golden Chest pool item.

Value / opening cost
Costs 1 key
Before you collect
An item is possible, but it is not guaranteed.
Effects, rules & related guides

A stone chest opened by an explosion, with the same reward possibilities as a Locked Chest.

Value / opening cost
Needs an explosion
Before you collect
Stand clear of the blast used to open it.
Effects, rules & related guides

A chest whose spikes damage you when you touch it to open it.

Value / opening cost
Normally costs ½ heart
Before you collect
Budget for the health payment before touching the spikes.
Effects, rules & related guides

Disguises itself as a brown chest, then reveals spikes when Isaac gets close.

Value / opening cost
Becomes spiked when approached
Before you collect
Approaching it can turn an apparently free chest into a health payment.
Effects, rules & related guides

A white chest that can close again and accept another key for a new payout.

Value / opening cost
1 key per opening
Before you collect
Repeated openings spend more keys, and the sequence can end without another reward.
Effects, rules & related guides
Old Chest in-game pickup

Chests

Old Chest

A worn chest that can reward Soul Hearts, trinkets, or an item from its own pool or the Angel Room pool.

Value / opening cost
Costs 1 key
Before you collect
It requires a key even though its worn appearance differs from a golden chest.
Effects, rules & related guides

A free chest focused on cards, runes, pills, and occasional Wooden Chest pool items.

Value / opening cost
Free to open
Before you collect
Opening it does not identify an unknown pill's effect for you.

Unlock: Defeat Mega Satan as Tainted Lazarus.

Effects, rules & related guides

An oversized locked chest with a variable key requirement and a large payout.

Value / opening cost
Costs 1–7 keys
Before you collect
One key may only make progress toward opening it.

Unlock: Defeat Mega Satan as Tainted Isaac.

Effects, rules & related guides

Approaching releases a Polty ghost that throws the chest at Isaac before it opens.

Value / opening cost
Ghost throws it before it opens
Before you collect
The closed or thrown chest deals half a heart of damage on contact.

Unlock: Defeat Mega Satan as Tainted Lost.

Effects, rules & related guides
Red Chest in-game pickup

Chests

Red Chest

Can release helpful pickups, friendly insects, an item, a teleport, or dangerous enemies and bombs.

Value / opening cost
Free opening; risky contents
Before you collect
Be ready to move as soon as it opens.
Effects, rules & related guides

The special chest in Mom's bedroom at Home gives Red Key on its first opening, then draws from Mom's Chest pool on later visits.

Value / opening cost
Free; found in Home
Before you collect
Its first-opening reward does not repeat on every Home run.
Effects, rules & related guides

A sack that opens into a small bundle of resource pickups.

Value / opening cost
Releases 1–4 pickups
Before you collect
Its random contents may not include the resource you need most.
Effects, rules & related guides

A dark sack with bombs, pills, Black Hearts, or Bone Hearts among its possible contents.

Value / opening cost
Releases 2–3 themed pickups
Before you collect
No more than one heart can come from a single Black Sack.

Unlock: Defeat Mega Satan as Tainted Judas.

Effects, rules & related guides

Continue learning your run

This directory covers health, money, keys, bombs, batteries, chests, and sacks in Repentance. Collectibles and trinkets have their own database. Cards, runes, soul stones, and pills have a full consumables catalog with effects and unlocks.