How you get here
Take an available Sheol trapdoor after the Womb finale. Progression and room access affect the available exit.
Prepare before the checkpoint
- For the standard Dark Room route, carry The Negative.
- Prepare for Satan's multiple phases before committing to the arena.
Related item rules: route tools and exceptions mentioned in this guide. Read each effect before relying on it.
Checkpoint and exit
Defeat Satan. Five Satan victories unlock The Negative for later runs.
The post-fight chest leads to Dark Room when the standard route requirement is met; otherwise it can end the run.
Enemies worth recognizing
Learn the attack cue before entering a crowded room. These are selected preparation references for this floor family, rather than a complete spawn list.
