In-game pickup line
“You're tearing me apart!”
Mechanics
What Leprosy does
- A hit creates an orbital body part, up to three at once.
- The orbitals block projectiles and deal contact damage, but repeated impacts can destroy them.
Achievement #368
How to unlock it
Clear Chapter 3 without taking damage.
Unlocking an item and finding it during a run are separate steps.
Explore more unlocksIn a run
Practical note
After a hit, position the new orbital between Isaac and incoming shots.
Reference
Game data and sources
The item ID, quality and pool listings, icon, game-file tags, and short pickup line come from the extracted Repentance files. This effect explanation is an editorial summary checked against the references below. Repentance+ can differ.
