In-game pickup line
“You feel prickly”
Mechanics
What Tooth and Nail does
- Every six seconds, Isaac becomes invincible for about one second.
- His sprite flashes before the protected interval begins.
In a run
Practical note
Watch the flash before crossing a hazardous path or closing in on an enemy.
Reference
Game data and sources
The item ID, quality and pool listings, icon, game-file tags, and short pickup line come from the extracted Repentance files. This effect explanation is an editorial summary checked against the references below. Repentance+ can differ.
